Any issues leaving a car in the US, while doing a sub trip from main trip?

I'm thinking about doing a road trip to the southern US in a few weeks and in the preliminary planning stages.

While there, I'm also thinking about doing a secondary trip, either a cruise, or flight to Asia/South America for a few weeks since flights are generally much cheaper there (depends on times/dates/costs as to what if anything I do). I would leave my car most likely with friends in south Florida or south Texas. After which I will return and continue with the road trip. Probably 4-8 weeks total away from home here.

Would there be any issue with this? A Canadian with no ties to US beyond the typical B2 visa or whatever? I know customs are particular about leaving things in the US, but would it be a problem if temporarily if I'm no longer in the country? I know "don't mention it" is an option, but I don't want to get into a situation where my car is there, but for whatever reason I'm not allowed back in. My lifestyle and travel habits are pretty irregular eg: "Um I got laid off 2 years ago so decided to go around the world a few times. Is that not something people do?", and I go to secondary more often than not, so I'm looking to play by the rules.

Looked online, could only find stuff about snowbirds leaving a car at their winter place.