Health & Wellness

Long Interspaced Nuclear Elements (LINE), Reverse Transcription of RNA to DNA and SARS-CoV-2

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Long Interspaced Nuclear Elements (LINE), Reverse Transcription of RNA to DNA and SARS-CoV-2

If that's possible then mRNA stuff can ended up in the DNA as well. Which can cause inflammations and therefore diseases (antibodies attacking the mutated cells).

SARS-CoV-2 RNA reverse-transcribed and integrated into the human genome
https://www.biorxiv.org/content/10.1101 ... 2.422516v1

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Sep 16, 2013
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the2ndme wrote: If that's possible then mRNA stuff can ended up in the DNA as well. Which can cause inflammations and therefore diseases (antibodies attacking the mutated cells).

SARS-CoV-2 RNA reverse-transcribed and integrated into the human genome
https://www.biorxiv.org/content/10.1101 ... 2.422516v1

It has been know for over a decade that under certain conditions mRNA can integrate into a genome. The most common condition for this is a certain stage of HIV. The article you linked mentions it. Nothing new. And the article itself is not about what you wrote. Has nothing to do with mRNA. Many viruses have integrated with human genome. One theory is that formation of placenta was induced by a virus giving rise to mammals, i.e., you and me. Don't worry, you wouldn't have existed without this process.
Deal Addict
Apr 29, 2018
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Yup, the human genome has parts of several viruses. Including a coronavirus that seems to have plagued us roughly 25000 years ago

https://www.medicalnewstoday.com/articl ... -evolution

Having those parts is how immunity works.

The human body depends on bacteria to do it's work and many even believe that the mitochondria may have been a completely different organism, that cells a long time ago, integrated within themselves as an energy source.
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[OP]
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alpovs wrote: It has been know for over a decade that under certain conditions mRNA can integrate into a genome. The most common condition for this is a certain stage of HIV. The article you linked mentions it. Nothing new. And the article itself is not about what you wrote. Has nothing to do with mRNA. Many viruses have integrated with human genome. One theory is that formation of placenta was induced by a virus giving rise to mammals, i.e., you and me. Don't worry, you wouldn't have existed without this process.
HIV has its own "reverse transcriptase". LINE is what is interesting.

According to this doctor, the experimental/emergency genetic "vaccines" are being treated like a typical "inactivated"/traditional vaccine by the regulatory people.

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This is probably related to this study. Nothing is certain at this moment but it is highly unlike and even if this is true, you still want to get the vaccine instead of the virus for the very same reason.
https://www.pnas.org/content/118/21/e2105968118

I would take comments of Robert Malone as grain of salt. He is not credited as the inventor of mRNA vaccine. He did published an important paper about the concept 30 years ago but the road of mRNA had went thru a lot to become the stage we are seeing today, a result of years of hard works from a few groups of scientists and some of them will probably be future Nobel prize recipients.
the2ndme wrote: If that's possible then mRNA stuff can ended up in the DNA as well. Which can cause inflammations and therefore diseases (antibodies attacking the mutated cells).

SARS-CoV-2 RNA reverse-transcribed and integrated into the human genome
https://www.biorxiv.org/content/10.1101 ... 2.422516v1

People around you may have weaken immune system (or live with one). Wear a mask in indoor settings if you have cold symptoms.
[OP]
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82 wrote: This is probably related to this study. Nothing is certain at this moment but it is highly unlike and even if this is true, you still want to get the vaccine instead of the virus for the very same reason.
https://www.pnas.org/content/118/21/e2105968118

I would take comments of Robert Malone as grain of salt. He is not credited as the inventor of mRNA vaccine. He did published an important paper about the concept 30 years ago but the road of mRNA had went thru a lot to become the stage we are seeing today, a result of years of hard works from a few groups of scientists and some of them will probably be future Nobel prize recipients.

No vaccine for some people and inactivated vaccine for others are the best options.

You try to discredit Robert Malone the person yet failed/did not try to dispute what he said in the video.
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I didn't watch this particular video, but I watched his early video with another famous person Bret Weinstein. He made some false claims about VARES. And he didn't provide any evidence that mRNA is not safe. The whole video is just like many typical propaganda video.

No vaccine is bad option, even for places with very low daily cases. Inactivated vaccines are fine but I don't know how effective are they to prevent Delta infection. Chile data shows they have advantage compared to its neighbors with low vaccination rate, but I expect mRNA would further reduce their daily cases. The good thing about inactivated vaccines are ease of transportation and administration, so they (and adenovirus vector vaccines) are important too.
the2ndme wrote: No vaccine for some people and inactivated vaccine for others are the best options.

You try to discredit Robert Malone the person yet failed/did not try to dispute what he said in the video.
People around you may have weaken immune system (or live with one). Wear a mask in indoor settings if you have cold symptoms.
[OP]
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Claiming propaganda is not a dispute. You are attacking the person not disputing what he said.

A healthy 20 year old taking an experimental genetic (or any) vaccine is stupid.

There is a reason this thread is under "health and wellness" not "other"/economics/politics.
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Don't see how the article with regards possible RNA reverse transcript to cause detection of "viral" particle via PCR test has to do with vaccine efficacy. They're just discussing a new discovery of a possible reason why people who recover from Covid19 still test positive. RNA is not mRNA....
[OP]
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coilz wrote: Don't see how the article with regards possible RNA reverse transcript to cause detection of "viral" particle via PCR test has to do with vaccine efficacy. They're just discussing a new discovery of a possible reason why people who recover from Covid19 still test positive. RNA is not mRNA....

RNA is RNA regardless of what letter is in front of it.

It's the potential for creating mutated cells which can leads to inflammations and then possibly diseases ( cancer for example) is the concern.
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the2ndme wrote: RNA is RNA regardless of what letter is in front of it.

It's the potential for creating mutated cells which can leads to inflammations and then possibly diseases ( cancer for example) is the concern.
Hogwash.

You can count on your fingers the number of situations where humans can transcribe RNA back to DNA. They are used in some species to transpose segments of DNA from area to the next using an RNA intermediary.

Humans are not retroviruses. LINE-1 RTs are leftover evolutionary fragment which lie dormant under most circumstances. The only places I have read about human RTs being active are in tumor cells and leukemias.
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mr_raider wrote: Hogwash.

You can count on your fingers the number of situations where humans can transcribe RNA back to DNA. They are used in some species to transpose segments of DNA from area to the next using an RNA intermediary.

Humans are not retroviruses. LINE-1 RTs are leftover evolutionary fragment which lie dormant under most circumstances. The only places I have read about human RTs being active are in tumor cells and leukemias.
I posted a study and talks relevant to the virus and genetic vaccines. Where is your study that disputes them? "Hogwash" is the best you can do?
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the2ndme wrote: RNA is RNA regardless of what letter is in front of it.

It's the potential for creating mutated cells which can leads to inflammations and then possibly diseases ( cancer for example) is the concern.
I should've said RNA is not the SAME as mRNA. mRNA is a type of RNA. These videos are just people trying to make a name for themselves for " discovering" something "novel" that sounds like it could be relevant if you just read the title, but with closer inspections require alot of speculation and big IFs. .. basically grasping at straws....

I don't think you'll get much of sympathetic voice here with regards to this discussion since even though it is the "Health and wellness" section of the forum. The topic will require some understanding of secondary education level of biology and beyond. This is afterall a deals forum. To get more lively discussion you should seek out more of an academic forum. Should have people with more expertise in this subject.

But if the point is to scare people from covid vaccines, I think the majority of people on this forum is pro-vaccine for the right reasons.
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the2ndme wrote: I posted a study and talks relevant to the virus and genetic vaccines. Where is your study that disputes them? "Hogwash" is the best you can do?
What degree do you have? You need studies for basic statements? Do you need a study to prove 2 + 2 = 4?
[OP]
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Oct 10, 2020
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coilz wrote: I should've said RNA is not the SAME as mRNA. mRNA is a type of RNA. These videos are just people trying to make a name for themselves for " discovering" something "novel" that sounds like it could be relevant if you just read the title, but with closer inspections require alot of speculation and big IFs. .. basically grasping at straws....

I don't think you'll get much of sympathetic voice here with regards to this discussion since even though it is the "Health and wellness" section of the forum. The topic will require some understanding of secondary education level of biology and beyond. This is afterall a deals forum. To get more lively discussion you should seek out more of an academic forum. Should have people with more expertise in this subject.

But if the point is to scare people from covid vaccines, I think the majority of people on this forum is pro-vaccine for the right reasons.

Philosophy (thought) is under "off-topic" I think.
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the2ndme wrote: RNA is RNA regardless of what letter is in front of it.
It shows you have no clue what you are talking about.
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the2ndme wrote: A healthy 20 year old taking an experimental genetic (or any) vaccine is stupid.
LOL! Where did you grow up? Have a look at the Ontario immunization schedule. We get at least 5 doses of vaccines against polio, diphtheria, pertussis, tetanus by the age 6. And others. You can credit this "stupid" "tradition" for not being disabled or dead now.
Deal Expert
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the2ndme wrote: I posted a study and talks relevant to the virus and genetic vaccines. Where is your study that disputes them? "Hogwash" is the best you can do?
The study shows that in cell cultures they can provoke human cells to back copy segments of viral RNA. To do that they have to prime the cells with certain chemicals.

They then hypothesize that this MiGHT happen in natural infection, which would explain prolonged positive PCR tests.

It's a massive leap then to claim that RNA from vaccines can be retro transcribed by the same mechanism and then somehow diffuse throughout the body and cause inflammation. RNA has minimal stability outside of cells and is degraded in a few hours.
[OP]
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Oct 10, 2020
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alpovs wrote: It shows you have no clue what you are talking about.
Again, "Long Interspaced Nuclear Elements (LINE), Reverse Transcription of RNA to DNA and SARS-CoV-2".



alpovs wrote: LOL! Where did you grow up? Have a look at the Ontario immunization schedule. We get at least 5 doses of vaccines against polio, diphtheria, pertussis, tetanus by the age 6. And others. You can credit this "stupid" "tradition" for not being disabled or dead now.

Again, "a healthy 20 year old taking an experimental genetic (or any) vaccine is stupid".
Deal Fanatic
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the2ndme wrote: RNA is RNA regardless of what letter is in front of it.
alpovs wrote: It shows you have no clue what you are talking about.
the2ndme wrote: Again, "Long Interspaced Nuclear Elements (LINE), Reverse Transcription of RNA to DNA and SARS-CoV-2".
Again it shows. You didn't make a single coherent statement about the link you posted. Read the paper.

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